Article ID Journal Published Year Pages File Type
1946781 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2010 12 Pages PDF
Abstract
►Identification of six clusters of genes strictly translationally regulated ►Control of mRNA expression and translation efficiency display distinct characteristics ►Translational control affects gene expression differentially in terms of kinetics, response intensity and class of genes also affected transcriptional regulation ►Translational control affects a smaller fraction of genes but was effective at earlier time-points as regulation on a transcriptional level ►56% of all the regulated genes by a factor of three are exclusively controlled by mRNA expression, whereas 16% of them are submitted solely to translational regulation and 28% are regulated by both mechanisms
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