Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1946861 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2010 | 15 Pages |
Abstract
It is well-established that plants use cytoplasmic, post-transcriptional gene silencing (PTGS) as a defense against RNA viruses and DNA virus transcripts. More recently, it has become clear that small RNA-directed methylation leading to transcriptional gene silencing (TGS) is also used as a defense against DNA virus chromatin. Here we use the DNA-containing geminiviruses as models to discuss what is currently known about both types of antiviral silencing, and viral suppression of PTGS and TGS as a counterdefense.
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Authors
Priya Raja, Jamie N. Wolf, David M. Bisaro,