Article ID Journal Published Year Pages File Type
1946941 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2009 11 Pages PDF
Abstract

The Drosophila system has proven a powerful tool to help unlock the regulatory processes that occur during specification and differentiation of the embryonic heart. In this review, we focus upon a temporal analysis of the molecular events that result in heart formation in Drosophila, with a particular emphasis upon how genomic and other cutting-edge approaches are being brought to bear upon the subject. We anticipate that systems-level approaches will contribute greatly to our comprehension of heart development and disease in the animal kingdom.

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