| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1946948 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2009 | 14 Pages |
Abstract
A link between the RNAi system and heterochromatin formation has been established in several model organisms including Schizosaccharomyces pombe and Arabidopsis thaliana. However, the data to support a role for small RNAs and the associated machinery in transcriptional gene silencing in animal systems is more tenuous. Using the S. pombe system as a model, we analyze the role of small RNA pathway components and associated small RNAs in regulating transposable elements and potentially directing heterochromatin formation at these elements in Drosophila melanogaster.
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Authors
Kathryn L. Huisinga, Sarah C.R. Elgin,