Tropisetron attenuated the anxiogenic effects of social isolation by modulating nitrergic system and mitochondrial function

Article ID	Journal	Published Year	Pages	File Type
1947372	Biochimica et Biophysica Acta (BBA) - General Subjects	2015	12 Pages	PDF

Abstract

Our results demonstrated tropisetron attenuated the anxiogenic effects of SIS by mitigation of the negative effects of nitric oxide on mitochondrial function.

Keywords

EPM SIS OFT O&NS open-field test Aminoguanidine Social isolation stress Oxidative and nitrosative stress Anxiety elevated plus maze Tropisetron Hole-board test HBT Mitochondria Nitric oxide Hippocampus

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Preview

Tropisetron attenuated the anxiogenic effects of social isolation by modulating nitrergic system and mitochondrial function

Authors

Shayan Amiri, Hossein Amini-Khoei, Arya Haj-Mirzaian, Maryam Rahimi-Balaei, Parvaneh Naserzadeh, AhmadReza Dehpour, Shahram Ejtemaei Mehr, Mir-Jamal Hosseini,