| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947405 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2015 | 13 Pages |
Abstract
Determining the roles of zebrafish CYP1s in physiology and toxicology depends on knowing the substrate selectivity of these enzymes.
Keywords
EROD7-Pentoxyresorufin O-depentylation7-PentoxyresorufinCYP or P450nanoscale molecular dynamics7-ethoxyresorufin O-deethylationPRODTetrolEFCMROD7-ethoxyresorufinLN2nAMDMOCMBCPORDMFAHRPAHMMCMFCDTTNADPH-cytochrome P450 reductaseN,N-dimethylformamideSubstrate selectivityBRODBenzo[a]pyreneMolecular dynamicsdithiothreitolCytochrome P450mass spectraYeastLiquid nitrogenPolycyclic aromatic hydrocarbonZebrafisharyl hydrocarbon receptor
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Authors
John J. Stegeman, Lars Behrendt, Bruce R. Woodin, Akira Kubota, Benjamin Lemaire, Denis Pompon, Jared V. Goldstone, Philippe Urban,