Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies

Article ID	Journal	Published Year	Pages	File Type
1947422	Biochimica et Biophysica Acta (BBA) - General Subjects	2015	12 Pages	PDF

Keywords

NOESY a.m.u.ESI Active site topology HMQC SAMs CyP TOCSY RMSD DEB A.U.MS/MS Nuclear Overhauser Effect SpectroscopY Arachidonic acid hydroxy-eicosatetraenoic acid Expression in yeast debrisoquine Molecular dynamics Retention time Cytochrome P450 Tandem mass spectrometry Total correlation spectroscopy root mean square deviation HETE heteronuclear multiple-quantum correlation atomic mass unit arbitrary units electrospray ionization

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies

Authors

Lionel Ducassou, Gabriella Jonasson, Laura Dhers, Nicolas Pietrancosta, Booma Ramassamy, Yun Xu-Li, Marie-Anne Loriot, Philippe Beaune, Gildas Bertho, Murielle Lombard, Daniel Mansuy, François André, Jean-Luc Boucher,