| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947442 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2015 | 15 Pages |
Abstract
The balance between electrophilic oxidative stress and protective biomolecular nucleophiles predisposes the evolution of modern life forms. Imbalances of the two can produce aberrant redox homeostasis with resultant pathologies. Understanding the pathways involved provides opportunities to consider interventional strategies. This article is part of a Special Issue entitled Redox regulation of differentiation and de-differentiation.
Keywords
TrxTGFβMSCHDACMDSNOSPPARγRNSSeCysIGF-1DUOXUPRHIFtrkAc-Jun NH2-terminal kinaseCREBTrxRmtROSTG2GSTPMKP-1thioredoxinsPRXGRxCCAAT/enhancer binding proteinsTBIEro1AMLER oxidoreductin 1GPXPDINACGSTHPCGSHHSCJnkBHANSCAPLatRAC/EBPN-acetylcysteineNADPH oxidasesNOxROSmitochondrial ROSTraumatic brain injuryall-trans retinoic acidinsulin-like growth factor-1Transforming Growth Factor BetaTissue transglutaminasethioredoxin reductasedual oxidaseRedoxelectron transport chainSODSelenocysteineMesenchymal stem cellsHematopoietic progenitor cellNeural stem cellsNitric oxide synthasesMyelodysplastic syndromesSuperoxide dismutaseendoplasmic reticulumhypoxia-inducible factorsFoxOacute myeloid leukemiaAPL, acute promyelocytic leukemiaCerebrospinal fluidCSFbutylated hydroxyanisolehistone deacetylasesETcUnfolded protein responseprotein disulfide isomeraseMitogen-activated protein kinase phosphatase-1PeroxiredoxinsGlutathioneGlutathione S-transferase Piglutathione S-transferaseglutathione reductaseGlutathione peroxidasesGlutaredoxinsreactive nitrogen speciesReactive oxygen species
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Authors
Zhi-Wei Ye, Jie Zhang, Danyelle M. Townsend, Kenneth D. Tew,