| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947472 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2015 | 7 Pages |
Abstract
The biophysical mechanisms, including variations in number of exocytotic release events, serotonin released per granule, and the membrane kinetics of exocytosis that underlie MC degranulation in response to CXCL10 and CCL5 were characterized at the single cell level. These findings clarify the function of ASM-derived chemokines as instigators of MC degranulation relative to classical mechanisms of MC stimulation.
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Authors
Benjamin M. Manning, Audrey F. Meyer, Sarah M. Gruba, Christy L. Haynes,