| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947593 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 10 Pages |
Abstract
⺠Oxidized quercetin inhibits fibrillization of α-synucein more strongly than quercetin does. ⺠Quercetin disaggregates α-synucein fibrils. ⺠Quercetin inhibits fibrillization and stabilizes oligomers. ⺠Quercetin binds with α-synucein in 1:1 ratio. ⺠Increased hydrophilicity of quercetin and α-synucein adducts accounts for inhibition.
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Authors
Min Zhu, Shubo Han, Anthony L. Fink,