| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947594 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 8 Pages |
Abstract
⺠Inhibiting glycolysis flux increases mitochondrial respiration ⺠Reducing net glycolytic ATP production increases mitochondrial respiration ⺠These studies define a specific, reciprocal glycolysis-respiration relationship ⺠This reciprocal relationship can be used to manipulate bioenergetics infrastructures
Keywords
Sirt1AMPKPGC1aTORC2mTORERKOCR2-DeoxyglucoseECAR2-DGAMP-activated protein kinaseHIF1aCrabtree effectPasteur effectRespirationhypoxia inducible factor 1 alphaOxidative phosphorylationMitochondriaOxygen consumption rateextracellular acidification ratemammalian target of rapamycinextracellular signal-regulated kinaseGlycolysisIodoacetate
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Authors
Russell H. Swerdlow, Lezi E., Daniel Aires, Jianghua Lu,