Article ID Journal Published Year Pages File Type
1947639 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 5 Pages PDF
Abstract

BackgroundOrganic electrochemical transistors (OECT) have been used as various types of biosensors with very high sensitivity. The OECTs show advantages of easy fabrication, low operational voltage, excellent flexibility and biocompatibility.MethodsOECT arrays based on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) were fabricated in poly(ethylene glycol) (PEG) microwells by physical delamination.ResultsThe OECTs show fast response time, stable channel current and excellent transistor characteristics. The PEG microwells can be used to trap cells on top of the OECTs, which will be important for the application of the OECT arrays as cell-based biosensors.General significanceThis technique provides a feasible way for high-throughput cell analysis based on transistor arrays. This article is part of a Special Issue entitled Organic Bioelectronics—Novel Applications in Biomedicine.

► Organic transistor microarrays were fabricated by physical delamination. ► The devices show fast response time and stable performance in electrolytes. ► Cancer cells can be trapped on the transistor arrays for cell analysis.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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