Article ID Journal Published Year Pages File Type
1947690 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 8 Pages PDF
Abstract
► Glycopeptides function as a molecular shuttle to hijack GAG biosynthetic pathway. ► Glycopeptides were incorporated into human articular chondrocytes. ► GAG-primed glycopeptides were enriched by mAb and characterized by HPLC and ESI-MS. ► Glycopeptides activated cell proliferation and production of type II collagen. ► This protocol allowed for real-time monitoring of GAG synthesis by culture cells.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Molecular shuttle between extracellular and cytoplasmic space allows for monitoring of GAG biosynthesis in human articular chondrocytes
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