| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947706 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 11 Pages |
Abstract
⺠S-nitrosylation (SNO) plays a crucial role in the control of gene transcription. ⺠SNO-regulated gene transcription evolved in bacteria as a means to detect NO stress. ⺠In eukaryotes, SNO primarily regulates transcription in the context of cell signaling. ⺠Nitrosylating and denitrosylating enzymes precisely regulate SNO-protein formation. ⺠Dysregulation of SNO-protein metabolism contributes to disease pathogenesis.
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Authors
Yonggang Sha, Harvey E. Marshall,