| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947744 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2011 | 6 Pages |
Abstract
⺠Streptonigrin as an inhibitor of β-catenin/Tcf transcription factor. ⺠Streptonigrin showed more evident cytotoxicity in β-catenin-activated cells. ⺠Inhibition effects depend on suppression of β-catenin/Tcf complexes with DNA.
Keywords
NF-κBβ-catenin/Tcf signalingGSKTBSTCBPTBEAPCTCFBCATBSIC50GAPDHSDSDMSOElectrophoretic mobility shift assayStreptonigrinInhibitordisheveledbicinchoninic acidTris buffered salineDßHDimethyl sulfoxidesodium dodecyl sulfateColorectal cancerEMSA یا electrophoretic mobility shift assay T-cell factorlymphoid enhancer factornuclear factor-κBLefhalf maximal inhibitory concentrationpolymerase chain reactionPCRCREB binding proteinCRCglyceraldehyde 3-phosphate dehydrogenase
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Authors
Seyeon Park, Sohyun Chun,