| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1947772 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 6 Pages |
Abstract
⺠Primary-amine oxidase mediates the adhesion of lymphocytes during inflammation. ⺠Glucosamine is widely used as a supplement for the treatment of arthritis. ⺠We show glucosamine to be a time-dependent inhibitor of PrAO activity. ⺠In vitro inhibition and binding were augmented in the presence of H2O2. ⺠Limitation: millimolar glucosamine concentrations required for inhibition in vitro.
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Authors
Aldo Olivieri, Keith F. Tipton, Jeff O'Sullivan,