Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1948043 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2009 | 4 Pages |
Abstract
The presented results demonstrate that reduction in the mobility of this region in Pdx1 proteins is required for formation of the in vivo dodecamer, negatively affecting the activity of Pdx1, opening the possibility of allosteric Pdx1 inhibitors.
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Authors
Julia Knöckel, Rositsa Jordanova, Ingrid B. Müller, Carsten Wrenger, Matthew R. Groves,