Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1948721 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2006 | 5 Pages |
Abstract
The effects of short time (15 min) exposure to hypoxia on rat cardiomyocytes (H9c2) were examined. Exposure to hypoxia inhibited cell death via activation of MEK/extracellular signal-regulated kinase (ERK). Further, exposure to hypoxia promoted cell growth by down-regulation of p27 and phosphorylation of cyclin-dependent kinase 2 (CDK2) and retinoblastoma protein (Rb).
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Authors
Rie Takahashi, Akiyuki Kawawa, Shunichiro Kubota,