| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1948812 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2006 | 4 Pages |
Abstract
We have examined fura 2-loaded purified peroxisomes under confocal microscope to prove that this mammalian organelle is a store of intracellular calcium pool. Presence of calcium channel and vanadate sensitive Ca2+-ATPase in the purified peroxisomal membrane has been demonstrated. We have further observed that machineries to maintain calcium pool in this mammalian organelle are impaired during infection caused by Leishmania donovani. Results reveal that peroxisomes have a merit to play a significant role in the metabolism of intracellular calcium.
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Authors
Bikramjit Raychaudhury, Shreedhara Gupta, Shouvik Banerjee, Salil C. Datta,