| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1949340 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 11 Pages |
Abstract
⺠Palmitic acid had a lower lipolysis rate than oleic acid in human myotubes. ⺠Compared to oleic acid, palmitic acid upregulated adipose triglyceride lipase. ⺠Palmitic acid was less accumulated than oleic acid. ⺠Related to oleic acid, palmitic acid upregulated β-oxidation and was oxidized more. ⺠The two abundant fatty acids have different metabolic fates in myotubes.
Keywords
SCD1MUFASFAECMSPALMMCPT1CD36/FATDGATGSEAHSLACSLFADS2CRATPDK4ASMslong-chain fatty acyl-CoA synthetaseFFAFDREPABSAbovine serum albuminAtglStearoyl-CoA desaturase 1Oleic acidEicosapentaenoic acidFatty acidFree fatty acidsaturated fatty acidfatty acid desaturase 2Polyunsaturated fatty acidmonounsaturated fatty acidPUFAfatty acid translocaseLipid oxidationGene Set Enrichment AnalysistriacylglycerolTAG یا triacylglycerols Scintillation proximity assayHADHAdiacylglycerolDiacylglycerol acyltransferaseDAGPhospholipidlipid dropletadipose triglyceride lipasehormone-sensitive lipaseLipolysisExtracellular matrixLinear mixed modelsfalse discovery ratePalmitic acidperilipinCarnitine palmitoyltransferase 1PLINcholesteryl ester
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Authors
Siril S. Bakke, Cedric Moro, NataÅ¡a NikoliÄ, Nina P. Hessvik, Pierre-Marie Badin, Line Lauvhaug, Katarina Fredriksson, Matthijs K.C. Hesselink, Mark V. Boekschoten, Sander Kersten, Michael Gaster, G. Hege Thoresen, Arild C. Rustan,