| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1949411 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 13 Pages |
Abstract
⺠We investigate genetic factors affecting HDL in a CASTxB6 F2 mouse cross. ⺠Network analysis identifies gene co-expression modules associated with HDL. ⺠Studies across independent data sets confirm robustness of identified modules. ⺠Using meta-analysis techniques we identify genes consistently associated with HDL. ⺠Causal testing implicates Wfdc2 and Hdac3 as novel genes affecting HDL levels.
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Authors
Peter Langfelder, Lawrence W. Castellani, Zhiqiang Zhou, Eric Paul, Richard Davis, Eric E. Schadt, Aldons J. Lusis, Steve Horvath, Margarete Mehrabian,