Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1949419 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 9 Pages |
Abstract
⺠HDL can regulate myelopoiesis through ABCA1 and ABCG1. ⺠HDL can prevent monocyte entry into the atherosclerotic lesion by inhibiting number and activation. ⺠HDL attenuates neutrophil activation and adhesion in acute models of inflammation. ⺠HDL modulates macrophage functions including migration, efferocytosis and TLR signaling.
Keywords
TLRJAK-2HSPCJanus Kinase 2STAT-3GM-CSFABCCBSLDLRHDLATP binding cassette transporterAtherosclerosisapoapolipoproteininterleukintoll like receptorhigh density lipoproteinMacrophagegranulocyte macrophage-colony stimulating factorSignal transducer and activator of transcription-3bone marrowMonocyteneutrophillow density lipoprotein receptor
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Authors
Andrew J. Murphy, Marit Westerterp, Laurent Yvan-Charvet, Alan R. Tall,