Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1949421 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 6 Pages |
Abstract
⺠The importance of ABCA1-apoA-I interaction in HDL formation is controversial. ⺠The ABCA1-apoA-I interaction is mediated via the electrostatic interaction. ⺠Lysine residues in the extracellular domains of ABCA1 contribute to the interaction. ⺠The direct ABCA1-apoA-I interaction is the first step in HDL formation.
Keywords
HDLLDLRECDABCA1HEKApoA-IGFPBHKFBSDMEMPBSABCBSAhigh-density lipoproteinDulbecco's modified Eagle's mediumbovine serum albuminApolipoprotein A-Ibaby hamster kidneyextracellular domainfetal bovine serumLDLPhosphate-buffered salinegreen fluorescent proteinhuman embryonic kidneyATP-binding cassetteLDL receptor
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Authors
Kohjiro Nagao, Yasuhisa Kimura, Kazumitsu Ueda,