Article ID Journal Published Year Pages File Type
1949436 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2012 8 Pages PDF
Abstract
► PKD phosphorylates PI4KIIIβ, CERT and OSBP, all of which are involved in lipid metabolism or trafficking. ► This molecular network coordinates non-vesicular and vesicular trafficking ensuring proper Golgi function. ► CERT-mediated non-vesicular ceramide transfer occurs at ER-Golgi membrane contact sites. ► Deregulated CERT is involved in human pathologies and its function is exploited by human pathogens.
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