Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1949436 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 8 Pages |
Abstract
⺠PKD phosphorylates PI4KIIIβ, CERT and OSBP, all of which are involved in lipid metabolism or trafficking. ⺠This molecular network coordinates non-vesicular and vesicular trafficking ensuring proper Golgi function. ⺠CERT-mediated non-vesicular ceramide transfer occurs at ER-Golgi membrane contact sites. ⺠Deregulated CERT is involved in human pathologies and its function is exploited by human pathogens.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Monilola A. Olayioye, Angelika Hausser,