| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1949470 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 10 Pages |
Abstract
⺠3-Methyl branched-chain fatty acids can be oxidized by α- and/or Ï-oxidation. ⺠The mechanism, enzymology and subcellular localization of α-oxidation has largely be resolved. ⺠The peroxisomal membrane is a semi-permeable membrane allowing the transport of some, but not all substrates and products of α-oxidation. ⺠The enzymology of the phytanic acid Ï-oxidation has largely been resolved. ⺠Stimulation of Ï-oxidation by bezafibrate reduces the accumulation of phytanic acid in Refsum mice.
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Authors
Ronald J.A. Wanders, Jasper Komen, Sacha Ferdinandusse,