| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1949473 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 13 Pages |
Abstract
⺠Overexpression of gankyrin induces hepatic steatosis in zebrafish. ⺠Transgenic gankyrin zebrafish (GK) have altered expression of 22 lipiogenic genes. ⺠miR-16, miR-27b, miR-122, and miR-126 are deregulated in the livers of GK fish. ⺠Overexpression of gankyrin induces hepatic lipoapoptosis and liver degeneration. ⺠Overexpression of gankyrin increases de novo free fatty acid synthesis pathways.
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Authors
Guor Mour Her, Chia-Chun Hsu, Jiann-Ruey Hong, Chi-Yu Lai, Meng-Chieh Hsu, Hsi-Wen Pang, Sheng-Kai Chan, Wan-Yu Pai,