Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1949484 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 11 Pages |
Abstract
⺠Acylcarnitines and sterols are useful markers of metabolic changes in mammals. ⺠We summarize how these compounds have been in the past analyzed by MS. ⺠We describe some ambient ionization - MS (AMS) techniques able to analyze in situ solid samples. ⺠We describe our AMS method for sterols and acylcarnitines analysis in dried blood or plasma spot. ⺠Direct analysis of DBS by AMS represents a new approach for in situ metabolic profiling.
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Authors
Gaetano Corso, Oceania D'Apolito, Daniela Garofalo, Giuseppe Paglia, Antonio Dello Russo,