| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1949577 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 10 Pages |
Abstract
⺠We model the intake, synthesis, transport, and degradation of cholesterol in mice. ⺠The model constructed can predict plasma cholesterol concentrations in knockout mice. ⺠A good prediction was given for 14 knockout strains, including Ldlrâ/â and Apoeâ/â. ⺠The model hints cholesterol transport to HDL to be independent on liver cholesterol.
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Authors
Niek C.A. van de Pas, Ruud A. Woutersen, Ben van Ommen, Ivonne M.C.M. Rietjens, Albert A. de Graaf,