Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1949843 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2009 | 7 Pages |
Abstract
Since the original discovery and structural elucidation of the mammalian phospholipase D (PLD), its potential to play a role in the lipid signalling pathway has attracted considerable interest. Now, it is generally accepted that different PLD isozymes are likely to serve diverse functions in membrane trafficking, endocytosis, exocytosis, cell growth, differentiation and actin cytoskeletal organization. In addition, PLDs are known to play a key role in neurite outgrowth, especially axon outgrowth, in neuronal cells.
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Authors
Yasunori Kanaho, Yuji Funakoshi, Hiroshi Hasegawa,