| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1951140 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2009 | 6 Pages |
Abstract
Ca2+-ATPase of muscle sarcoplasmic reticulum is an ATP-powered Ca2+-pump that establishes a > 10,000 fold concentration gradient across the membrane. Its crystal structures have been determined for 9 different states that cover nearly the entire reaction cycle. Presented here is a brief structural account of the ion pumping process, with emphasis on why the structure has to be so.
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Authors
Chikashi Toyoshima,