| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1951158 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2009 | 5 Pages |
Abstract
Prostate cancer is the second cancer-related cause of death. Nowadays, the aim of treatments is to decrease the effects of androgens on this organ. Unfortunately, over time, patients develop an androgen-independent cancer with a fatal outcome. The main features of late stage prostate cancer are an increased cell proliferation and apoptosis resistance. It is well known that calcium (Ca2+), a ubiquitous secondary messenger, is involved in several processes such as apoptosis and proliferation. In this mini review, we will focus on the changes in Ca2+ homeostasis of prostate cancer epithelial cells during prostate cancer evolution.
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Authors
Matthieu Flourakis, Natacha Prevarskaya,