Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1951342 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2009 | 9 Pages |
Abstract
Respiratory deficient mutants of Saccharomyces cerevisiae have been instrumental in identifying an increasing number of nuclear gene products that promote pre- and post-translational steps of the pathway responsible for biogenesis of the mitochondrial ATP synthase. In this article we have attempted to marshal current information about the functions of such accessory factors and the roles they play in expression and assembly of the mitochondrially encoded subunits of the ATP synthase. We also discuss evidence that the ATP synthase may be built up from three separate modules corresponding to the F1 ATPase, the stator and F0.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Malgorzata Rak, Xiaomei Zeng, Jean-Jacques Brière, Alexander Tzagoloff,