| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1952986 | Biochimie | 2008 | 25 Pages |
Abstract
Telomeres and telomerase represent, at least in theory, an extremely attractive target for cancer therapy. The objective of this review is to present the latest view on the mechanism(s) of action of telomerase inhibitors, with an emphasis on a specific class of telomere ligands called G-quadruplex ligands, and to discuss their potential use in oncology.
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Authors
Anne De Cian, Laurent Lacroix, Céline Douarre, Nassima Temime-Smaali, Chantal Trentesaux, Jean-François Riou, Jean-Louis Mergny,