| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1956990 | Biophysical Journal | 2005 | 4 Pages |
Abstract
Images obtained with a laser-scanning microscope contain a time structure that can be exploited to measure fast dynamics of molecules in solution and in cells. The spatial correlation approach provides a simple algorithm to extract this information. We describe the analysis used to process laser-scanning images of solutions and cells to obtain molecular diffusion constant in the microsecond to second timescale.
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Authors
Michelle A. Digman, Parijat Sengupta, Paul W. Wiseman, Claire M. Brown, Alan R. Horwitz, Enrico Gratton,