Article ID Journal Published Year Pages File Type
1963490 Cellular Signalling 2013 10 Pages PDF
Abstract
► Phosphorylated Hsp27 mimics activate p53/p21. ► Phosphorylated Hsp27 facilitate p53 nuclear importing in an ATM-dependent manner. ► Hsp27 facilitate p53 degradation in MDM2 dependent manner. ► Phosphorylated Hsp27 facilitate interaction of Hsp27-p53-MDM2. ► Phosphorylated Hsp27 regulated p53 pathway and cell survival.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , , , , , , , ,