| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1963515 | Cellular Signalling | 2013 | 15 Pages |
Abstract
⺠Inhibition of Notch signaling fights against endothelial oxidative stress injury (OSI). ⺠Curcumin can attenuate endothelial OSI. ⺠The protective effects of curcumin against endothelial OSI are in part via Notch1 inhibition.
Keywords
OSI3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromideOxidative stress injuryMDAMethane dicarboxylic aldehydeDAPIDCFH-DAHUVECSHRT2′,7′-dichlorofluorescein diacetate4′,6-diamino-2-phenylindoleGSH-PxMTTROSHydrogen peroxidePuromycin aminonucleosidestandard deviationterminal deoxynucleotidyl transferase dUTP nick-end labelingTUNELSODEndothelial cellHuman umbilical vein endothelial cellslactate dehydrogenaseLDHNotch signaling pathwayhairy and enhancer of split 1Hes1H2O2optical densityCurcuminglutathione peroxidaseReactive oxygen species
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Authors
Yang Yang, Weixun Duan, Zhenxin Liang, Wei Yi, Juanjuan Yan, Ning Wang, Yue Li, Wensheng Chen, Shiqiang Yu, Zhenxiao Jin, Dinghua Yi,