Article ID Journal Published Year Pages File Type
1963546 Cellular Signalling 2013 9 Pages PDF
Abstract
► Salubrinal differentially regulates osteoblast and osteoclast differentiations. ► eIF2α phosphorylation down-regulates NFATc1 during RANKL induced osteoclastogenesis. ► ATF4 up-regulation contributes osteoblast differentiation in response to salubrinal. ► Salubrinal prevents bone destruction induced by RANKL in vivo.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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