Article ID Journal Published Year Pages File Type
1963621 Cellular Signalling 2012 7 Pages PDF
Abstract
► CaM binds directly to β-PIX in a Ca2 +-dependent manner. ► Fluorescence measurements and ITC show a KD ≤ 10 μM for the CaM-β-PIX interaction. ► CaM is essential for interaction of β-PIX with Cbl, to form a multi-protein complex. ► Cbl-mediated RTK ubiquitination is Ca2 +/CaM dependent.
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