Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1963621 | Cellular Signalling | 2012 | 7 Pages |
Abstract
⺠CaM binds directly to β-PIX in a Ca2 +-dependent manner. ⺠Fluorescence measurements and ITC show a KD â¤Â 10 μM for the CaM-β-PIX interaction. ⺠CaM is essential for interaction of β-PIX with Cbl, to form a multi-protein complex. ⺠Cbl-mediated RTK ubiquitination is Ca2 +/CaM dependent.
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Authors
Vinay K. Singh, Kim Munro, Zongchao Jia,