| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1964696 | Cellular Signalling | 2012 | 8 Pages |
Abstract
⺠Ang II promotes cell survival through upregulation and activation of SGK1. ⺠Ang II increases the levels of SGK1 via calcium and tyrosine kinase signalling. ⺠Ang II increases the phosphorylation of SGK1 via an mTOR-dependent mechanism. ⺠SGK1 promotes cell survival by mediating the phosphorylation of FOXO3A at Thr32. ⺠These are novel mechanisms by which Ang II can mediate cell survival.
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Authors
Rebekah Baskin, Peter P. Sayeski,