| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1964702 | Cellular Signalling | 2012 | 9 Pages |
Abstract
⺠The cholesterol metabolite 27-hydroxycholesterol induces endoplasmic reticulum stress. ⺠Endoplasmic reticulum stress activates CHOP and down-regulates C/EBPα expression. ⺠Down-regulation of C/EBPα negatively regulates the adipocytokine leptin. ⺠siRNA to CHOP and C/EBPα over-expression preclude down-regulation of leptin.
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Authors
Gurdeep Marwarha, Bhanu Dasari, Othman Ghribi,