| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1964709 | Cellular Signalling | 2012 | 11 Pages |
Abstract
⺠The MMP-9 acts as a processing enzyme for CD44 cleavage. ⺠Activated MMP-9 protein induced CD44 cleavage in vitro. ⺠Transcriptional knockdown of either CD44 or MMP-9 inhibits cell migration. ⺠Supplementation of MMP-9 resumed shMMP-9 inhibited CD44 cleavage and migration. ⺠CD44 extracellular domain plays a critical role in cell migration and invasion.
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Authors
Chandramu Chetty, Sravan K. Vanamala, Christopher S. Gondi, Dzung H. Dinh, Meena Gujrati, Jasti S. Rao,