Article ID Journal Published Year Pages File Type
1965077 Clinica Chimica Acta 2016 6 Pages PDF
Abstract
We identified and characterized a novel intronic mutation in the MSX1 gene in a large Chinese pedigree, adding to the small repertoire of MSX1 mutations associated with autosomal dominant tooth agenesis. We hypothesize that the variable degree of tooth agenesis observed in each affected individual may be due to sub-optimal levels of MSX1 expression during critical stages tooth development.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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