| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1965450 | Clinica Chimica Acta | 2014 | 7 Pages |
Abstract
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migration, invasion and metastasis. In this review, the associations of the expression and localization of Gal-3 as well as its potential action mechanism in tumorigenesis in a variety of cancers were summarized and concluded. Gal-3 is gaining its attraction as a potential new biomarker for the diagnosis, treatment and prognosis of certain tumors.
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Authors
Lin Song, Jian-wu Tang, Lawrence Owusu, Ming-Zhong Sun, Jun Wu, Jun Zhang,