Article ID Journal Published Year Pages File Type
1967681 Clinica Chimica Acta 2007 8 Pages PDF
Abstract

von Willebrand factor is a multimeric plasma protein that mediates platelet adhesion as well as platelet aggregation at sites of vascular injury and, moreover, acts as a carrier of factor VIII. Its deficiency is associated with a bleeding tendency. The progresses in the pathophysiology, diagnosis and management of inherited von Willebrand disease and acquired von Willebrand syndrome will be discussed in this review.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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