Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1967681 | Clinica Chimica Acta | 2007 | 8 Pages |
Abstract
von Willebrand factor is a multimeric plasma protein that mediates platelet adhesion as well as platelet aggregation at sites of vascular injury and, moreover, acts as a carrier of factor VIII. Its deficiency is associated with a bleeding tendency. The progresses in the pathophysiology, diagnosis and management of inherited von Willebrand disease and acquired von Willebrand syndrome will be discussed in this review.
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Authors
Massimo Franchini, Giuseppe Lippi,