Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1969994 | Clinical Biochemistry | 2008 | 8 Pages |
Abstract
This study clearly demonstrates that NSAIDs can down-regulate the PA/plasmin system and gelatinases expression during the early stage of knee OA, thereby possibly affect the structural progression of the disease. This inhibition seems to be independent selection of COX-1 and COX-2.
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Authors
Shun-Fa Yang, Yih-Shou Hsieh, Ko-Huang Lue, Shu-Chen Chu, I-Chang Chang, Ko-Hsiu Lu,