| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1970216 | Clinical Biochemistry | 2007 | 8 Pages |
Abstract
In this study, only gastritis was found to be associated with significant oxidative stress marker expression of TNF-α and IL-8 that was also related to H. pylori virulence, suggesting that they are the main oxidant stress markers responsible to trigger an increase in ROS level that contributes to decrease the expression of the MnSOD and GPX.
Keywords
GPXIL-8VacAMnSODIFN-γIL-10IL-1βIL-12iNOSGAPDHCATBHIIL-6NOX1cagANADPH oxidase 1O2−ROSHydrogen peroxideOxidative damageAntioxidant enzymesinflammationinterferon-γinterleukin-12Interleukin-10interleukin-6Interleukin-1βbrain heart infusiontumor necrosis factor-αGastric ulcerGastric carcinomainducible nitric oxide synthaseSuperoxideBacterial virulence factorsTNF-αmanganese-superoxide dismutaseNitric oxideH2O2cytotoxin-associated gene ACatalaseGastritisglutathione peroxidaseglyceraldehyde-3 phosphate dehydrogenaseReactive oxygen species
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Authors
Amanda C. Augusto, Fernanda Miguel, Sérgio Mendonça, José Jr., Sonia A. Gurgueira,