| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1970236 | Clinical Biochemistry | 2007 | 4 Pages |
Abstract
Objectives:To investigate the analytical interference between serum Tg and TgAb.Design and methods:Tg and TgAb were measured on an automated chemiluminescent immunoassay system in mixed sera from DTC patients and individual samples spiked with exogenous Tg.Results:Tg and TgAb recoveries in mixed patient samples were inversely correlated with expected TgAb or Tg concentrations, respectively. Impaired TgAb recoveries were also found in 50% (10/20) samples with high Tg in the exogenous recovery tests.Conclusions:Mutual but not equal analytical interference between Tg and TgAb is present and concentration-dependent with interpatient variability.
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Authors
Yunchao Gao, Zhibin Yuan, Yongli Yu, Hankui Lu,