Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1970847 | Clinical Biochemistry | 2011 | 4 Pages |
Abstract
ObjectivesTo evaluate carbonyl groups (CG) serum levels in B-chronic lymphocytic leukemia (B-CLL) patients.Design and methodsCG serum levels were assessed in 48 B-CLL patients and in 30 control subjects.ResultsCG were increased in B-CLL patients. We found a positive correlation between CG with CD38 expression and a negative correlation with ZAP 70 expression.ConclusionsB-CLL patients displayed an unbalance of the oxidative stress. CG serum levels could be considered as a prognostic factor in B-CLL.
► CG serum levels in B-CLL patients. ► CG were increased in B-CLL patients. ► Correlation with prognostic factors.
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Authors
Caterina Musolino, Alessandro Allegra, Andrea Alonci, Antonella Saija, Sabina Russo, Antonino Cannavò, Mariateresa Cristani, Raffaella Centorrino, Salvatore Saitta, Angela Alibrandi, Sebastiano Gangemi,