Article ID Journal Published Year Pages File Type
1971367 Clinical Biochemistry 2008 7 Pages PDF
Abstract

ObjectivesTo compare ion exchange and boronate affinity chromatography for HbA1c estimation in patients with type I and II diabetes having hemoglobin D.Design and methodsSystems based on ion exchange and boronate affinity chromatography were evaluated and compared for their performance for HbA1c estimation in patients with homozygous and heterozygous D disease.ResultsBoronate affinity chromatography shows least interference by HbD in heterozygous as well as homozygous diabetic patients for HbA1c estimation.ConclusionsThe use of boronate affinity chromatography was found to be helpful in evaluating glycemic control in diabetic subjects with HbD.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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