| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1971712 | Clinical Biochemistry | 2007 | 4 Pages |
Abstract
Objectives:Lysophospholipase D (lysoPLD)/autotaxin regulates the blood levels of lysophosphatidic acid (LPA), and we designed a serum lysoPLD assay for use in clinical laboratory testing.Design and methods:LysoPLD activity was assessed based on the amount of choline released with lysophosphatidylcholine as the substrate.Results and conclusions:It was confirmed that the lysoPLD assay can be applied to clinical laboratory testing. The serum lysoPLD activity in healthy female subjects was significantly higher than that in the male subjects.
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Authors
Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Minoru Tozuka, Mitsumasa Okada, Shinya Aoki, Junken Aoki, Hiroyuki Arai, Hitoshi Ikeda, Yutaka Yatomi,